Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | PLAA | contributors: mct/npt - updated : 06-06-2017 |
HGNC name | phospholipase A2-activating protein |
HGNC id | 9043 |
|
DNA |
TYPE | functioning gene |
STRUCTURE | 44.10 kb 13 Exon(s) |
10 Kb 5' upstream gene genomic sequence study |
---|
MAPPING | cloned | Y | linked | status | provisional |
Map | pter - IFN1@ - CDKN2A - CDKN2B - D9S1870 - D9S171 - D9S1679 - D9S265 - D9S259 - PLAA - cen |
Authors | Beatty (99) |
RNA |
TRANSCRIPTS | type | messenger |
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|
EXPRESSION |
Type | widely |
expressed in | (based on citations) | ||||||||||||||||||||||||||||||||||||||||
organ(s) |
|
cell lineage
cell lines
| fluid/secretion
| |
at STAGE |
PROTEIN |
PHYSICAL PROPERTIES
STRUCTURE
| |
HOMOLOGY |
interspecies | ortholog to yeast Doa1/Ufd3 |
Homologene |
FAMILY | |
|
CATEGORY | enzyme |
SUBCELLULAR LOCALIZATION | extracellular |
intracellular | |
intracellular,cytoplasm | |
intracellular,nucleus |
CELLULAR PROCESS |
PHYSIOLOGICAL PROCESS |
PATHWAY |
metabolism |
signaling |
a component |
INTERACTION |
DNA |
RNA |
small molecule |
cell & other |
REGULATION |
induced by | TNF-alpha can perpetuate inflammation by enhancing activation of PLA(2) and NF-kappaB |
ASSOCIATED DISORDERS |
corresponding disease(s) | PLAAND |
Susceptibility |
Variant & Polymorphism
| |
Candidate gene
Marker
| Therapy target
|
| |
ANIMAL & CELL MODELS |