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FLASH GENE
Symbol MORC1 contributors: - updated : 13-03-2006
HGNC name MORC family CW-type zinc finger 1
HGNC id 7198
DNA
TYPE functioning gene
STRUCTURE 159.00 kb     28 Exon(s)
MAPPING cloned Y linked   status provisional
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Reproductivemale systemtestis  specific
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a bipartite nuclear localization signal
  • two coiled-coil domains
  • a leucine zipper motif
  • HOMOLOGY
    interspecies homolog to murine Microrchidia
    Homologene
    FAMILY
    CATEGORY unknown/unspecified
    SUBCELLULAR LOCALIZATION
    basic FUNCTION may have a role in spermatogenesis
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS reproduction/sex
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule metal binding,
    ion Zn2+
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS
    homozygous morc -/- males are infertile and have grossly reduced testicular mass, whereas morc -/- females are normal