basic FUNCTION
| eukaryotic translation initiation factor |
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stabilizing initiator Met tRNA (TRIMs) binding to 40S subunits |
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regulates cell growth and viability, and overexpression of the gene may provide growth advantage to the cancer cells |
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promoting the association of Met-tRNA and mRNA |
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high EIF3H levels directly stimulate protein synthesis, resulting in the establishment and maintenance of the malignant state in cells |
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plays a central role in translation initiation |
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has specific as well as redundant functions during early development |