basic FUNCTION
| involved in the establishment of structures of the visual system |
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essential for the correct differentiation of ependyma and astrocytes |
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potent regulator of subventricular zone organization and NSC proliferation, with important consequences on postnatal neurogenesis |
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homeodomain transcription factor with a role in eye and optic chiasm development, causing the rostral oral ectoderm to form an ectopic fold that eventually develops into a separate second pituitary with all the pituitary cell types and neuronal fibers characteristic of the normal pituitary |
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might be involved in the pathogenesis of optic nerve dysplasia |