basic FUNCTION
| transcription factor that functions as a repressor for GATA-mediated transcription, androgen-repressible, apoptosis associated |
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repressing transcription of genes involved in chondrocyte differentiation |
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regulator of chondrocytes proliferation and survival through the control of STAT3 expression (Suemoto 2007) |
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plays a pivotal role downstream of GDF5 signaling in promoting chondrogenesis and apoptosis of ATDC5 cells (Itoh 2008) |
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zinc binding involved in skeletal development |
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regulates osteocalcin expression and modulates mineralized bone matrix formation (Piscopo 2009) |
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is a novel regulator of the Wnt signaling pathway and of early hair follicle progenitors in the developing vibrissa follicle |
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TRPS1 directly represses expression of the hair follicle stem cell regulator SOX9 to control proliferation of the follicle epithelium |
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multi zinc-finger nuclear regulator of chondrocyte proliferation and differentiation |
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acts as regulator of histone deacetylation |
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GATA-type transcription factor that acts as a transcriptional repressor |
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is required for odontoblast maturation by supporting expression of genes crucial for initiating the mineralization process, and represses the function of mature cells and, consequently, restricts the extent of extracellular matrix mineralization |
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atypical GATA factor, modulating cell proliferation and controling cell cycle progression |
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acts as a central hub in the control of cell cycle and proliferation during cancer development |
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is a potent regulator of proliferation, differentiation, and apoptosis |