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FLASH GENE
Symbol MRPS30 contributors: mct/npt - updated : 12-07-2008
HGNC name mitochondrial ribosomal protein S30
HGNC id 8769
DNA
TYPE functioning gene
STRUCTURE 6.00 kb     5 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
Physical map
OXCT 5p13 3-oxoacid CoA transferase LOC285636 5p13.1 hypothetical protein LOC285636 FBXO4 5p12 F-box only protein 4 LOC391779 5 similar to 40S ribosomal protein SA (P40) (34/67 kDa laminin receptor) (Colon carcinoma laminin-binding protein) (NEM/1CHD4) (Multidrug resistance-associated protein MGr1-Ag) GHR 5p13.1-p12 growth hormone receptor LOC389287 5 similar to synaptonemal complex protein SYP-1, SYnaPsis in meiosis abnormal SYP-1 (56.6 kD) (syp-1) SEPP1 5q31 selenoprotein P, plasma, 1 LOC391780 5 similar to peptidyl-Pro cis trans isomerase LOC340065 5p13.1 hypothetical LOC340065 LOC389288 5 LOC389288 LOC389289 5 similar to annexin II receptor LOC153684 5p13.1 hypothetical protein LOC153684 FLJ90723 5p13.1 hypothetical protein FLJ90723 FLJ10246 5p13.1 hypothetical protein FLJ10246 MGC42105 5p13.1 hypothetical protein MGC42105 HMGCS1 5p14-p13 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 (soluble) CCL28 5p12 chemokine (C-C motif) ligand 28 FLJ21657 5p12 hypothetical protein FLJ21657 FLJ32363 5p12 FLJ32363 protein PAIP1 5q31.1-q31.3 Homo sapiens polyadenylate binding protein-interacting protein 1 (PAIP1), transcript variant 3, mRNA. NNT 5p13.1-cen nicotinamide nucleotide transhydrogenase FGF10 5p13-p12 fibroblast growth factor 10 MRPS30 5q11 mitochondrial ribosomal protein S30 HCN1 19p13.3 hyperpolarization activated cyclic nucleotide-gated potassium channel 1
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
5 - 1686 50.4 439 - Zhang (2003)
EXPRESSION
Type widely
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Cardiovascularheart   predominantly
Digestiveliver    
Hearing/Equilibriumear   highly
Lymphoid/Immunelymph node   highly
Reproductivefemale systemuteruscervix highly
Urinarykidney    
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Blood / Hematopoietic    
Muscularstriatumcardiac  
Muscularstriatumskeletal  
cells
SystemCellPubmedSpeciesStageRna symbol
Blood/Hematopoieticleukocyte
cell lineage
cell lines
fluid/secretion
at STAGE
physiological period pregnancy
Text placenta
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • not showing any known motif or protein domain
  • specific to mitochondrial ribosomes not in prokaryotes
  • HOMOLOGY
    interspecies homolog to murine Mrps30
    homolog to E.Coli 30S subunit proteins
    intraspecies homolog to G-gallu proapoptotic protein p52
    Homologene
    FAMILY
  • ribosomal protein S30P family
  • CATEGORY regulatory , RNA associated
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,mitochondria,matrix
    text mitochondrial ribosome
    basic FUNCTION
  • mitochondrial proteins biosynthesis
  • ribosomal structure and biogenesis
  • involved in cellular apoptotic signaling pathway
  • CELLULAR PROCESS cell life, cell death/apoptosis
    protein, translation/synthesis
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
  • component of the small subunit (28S) of the mitochondrial ribosome, including two RNA molecules and 78 MRPs among which 31 proteins for the small subunit
  • INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility to estrogen receptor positive breast cancer with good prognosis
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS