basic FUNCTION
| having a function in promoting its nuclear entry and the catalytic activity may potentially regulate its nuclear import through autophosphorylation and/or interaction with another protein (Rey 2006) |
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regulates protein transport from the Golgi to the plasma membrane and may regulate VAMP2 vesicle trafficking by facilitating its recruitment to the target membrane( Lu 2007) |
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plays a role in numerous processes including cell proliferation, cell survival, immune cell signaling, gene expression, vesicle trafficking, and neuronal development (Kunkel 2009) |
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PRKD3 regulates a distinct set of substrates to fulfill such functions, which is in accordance with our findings that PRKD3 selectively phosphorylates GIT1 to enhance cell spreading and motility |