Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | LANCL1 | contributors: mct - updated : 28-03-2009 |
HGNC name | LanC lantibiotic synthetase component C-like 1 (bacterial) |
HGNC id | 6508 |
|
DNA |
TYPE | functioning gene |
STRUCTURE | 45.46 kb 10 Exon(s) |
10 Kb 5' upstream gene genomic sequence study |
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regulatory sequence | Promoter |
Binding site | |
text structure | within the potential promoter regions, several consensus sequences for ubiquitous and tissue-specific transcription factors are present (Mayer 2001) |
MAPPING | cloned | Y | linked | status | confirmed |
Map | cen - D2S355 - D2S154 - CPS1 - MYL1 - LANCL1 - ERBB4 - D2S371 - D2S143 - FN1 - D2S137 - qter |
Authors | GeneMap (98) |
RNA |
TRANSCRIPTS | type | messenger |
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text | Variants 1, 2 and 3 encode the same protein |
|
EXPRESSION |
Type | ubiquitous |
expressed in | (based on citations) |
organ(s) |
tissue |
|
cells |
|
cell lineage
cell lines
| fluid/secretion
| |
at STAGE |
PROTEIN |
PHYSICAL PROPERTIES | Hydrophobic | |
STRUCTURE |
motifs/domains
| |
|
HOMOLOGY |
interspecies | homolog to rattus Lancl1 (91.5 pc) |
homolog to murine Lancl1 (91.5 pc) | |
homolog to a prokaryotic enzyme responsible for the synthesis of thioether (lanthionine) cross-linking within nascent polypeptide chains, yielding macrocyclic proteins with potent microbicidal activity (Chung 2007) |
Homologene |
FAMILY | |
|
CATEGORY | receptor membrane G |
SUBCELLULAR LOCALIZATION | plasma membrane |
intracellular | |
intracellular,cytoplasm |
basic FUNCTION | |
| |
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