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FLASH GENE
Symbol ACAA2 contributors: mct - updated : 30-08-2008
HGNC name acetyl-Coenzyme A acyltransferase 2
HGNC id 83
DNA
TYPE functioning gene
STRUCTURE 30.00 kb     10 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
Map cen - D18S460 - [D18S1118 - D18S470 ] - D18S474 - qter
Authors Gene Map (98)
Text [ACAA2 ]
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
10 - 1952 41 397 - Cao (2008)
EXPRESSION
Type ubiquitous
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Cardiovascularheart   highly
Endocrinethyroid   highly
Urinarykidney   highly
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a non-cleavable amino-terminal targeting signal
  • HOMOLOGY
    Homologene
    FAMILY
  • thiolase family
  • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,mitochondria
    basic FUNCTION
  • acetyl-CoA acyltransferase 2, mitochondrial-3-oxoacyl-coenzyme A, thiolase, concluding the step of fatty acid beta oxidation
  • catalyzes the last step of the mitochondrial fatty acid beta-oxidation spiral
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein functional BNIP3 binding partner (possible linkage between fatty acid metabolism and apoptosis of cells)
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS