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FLASH GENE
Symbol KDELR3 contributors: mlc/np - updated : 05-11-2007
HGNC name KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
HGNC id 6306
DNA
TYPE functioning gene
STRUCTURE 15.00 kb     5 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked   status confirmed
Map cen - D22S277 - IL2RB - KDELR3 - D22S283 - qter
Authors Gene Map (98)
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
5 splicing 1705 25 214 - Makhina
- splicing 920 - 220 - Makhina
EXPRESSION
Type ubiquitous
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Cardiovascularheart   highly
Endocrineneuroendocrinepituitary  highly
Hearing/Equilibriumear   highly
Respiratoryrespiratory tractlarynx  highly
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
interspecies ortholog to yeast S.cerevisiae ERD2
intraspecies homolog to KDELR2
Homologene
FAMILY
  • KDEL receptor family
  • ERD2 family
  • CATEGORY receptor , transport
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,lumen
    intracellular,cytoplasm,organelle,membrane
    intracellular,cytoplasm,organelle,endoplasmic reticulum ,rough,smooth
    basic FUNCTION
  • endoplasmic reticulum protein retention receptor 3
  • allowing the retrieval of proteins from Golgi complex to ER
  • mediates a retrieval mechanism contributing to quality control at the endoplasmic reticulum
  • CELLULAR PROCESS protein
    PHYSIOLOGICAL PROCESS
    text protein
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS