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FLASH GENE
Symbol WARS2 contributors: mct - updated : 30-05-2007
HGNC name tryptophanyl tRNA synthetase 2 (mitochondrial)
HGNC id 12730
DNA
TYPE anonymous DNA segment
STRUCTURE 109.00 kb     6 Exon(s)
Genomic sequence alignment details
10 Kb 5' upstream gene genomic sequence study
regulatory sequence Promoter
text structure IFN-gamma-sensitive promoter
MAPPING cloned Y linked   status provisional
Map pter - D1S252 - D1S453 - WARS2 - D1S514 - cen
Authors Martinez-Dominguez (98)
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
- - 2806 - 360 - Oh
- - 2835 - 220 - Oh
EXPRESSION
Type ubiquitous
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Lymphoid/Immunelymph node   highly
Reproductivefemale systemuteruscervix highly
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
signal peptide for mitochondrial import
HOMOLOGY
interspecies homolog to bacterial tryptophanyl tRNA synthetase
Homologene
FAMILY
CATEGORY enzyme
SUBCELLULAR LOCALIZATION     intracellular
intracellular,cytoplasm,organelle,mitochondria
basic FUNCTION unknown
CELLULAR PROCESS
PHYSIOLOGICAL PROCESS
PATHWAY
metabolism
signaling
a component
INTERACTION
DNA
RNA
small molecule
protein
cell & other
REGULATION
Other regulated by gamma-interferon (IFN-gamma), an anti-proliferative cytokine known to stimulate the expression of other anti-angiogenic factors
ASSOCIATED DISORDERS
ANIMAL & CELL MODELS