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FLASH GENE
Symbol GALR3 contributors: mct - updated : 02-10-2007
HGNC name galanin receptor 3
HGNC id 4134
DNA
TYPE functioning gene
STRUCTURE 2.00 kb     2 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked   status confirmed
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type restricted
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Endocrinepancreas    
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Epithelialsecretoryglandularexocrine 
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
seven transmembrane segments (7TM) receptor
HOMOLOGY
Homologene
FAMILY G protein coupled receptor superfamily
CATEGORY receptor
SUBCELLULAR LOCALIZATION     plasma membrane
basic FUNCTION
  • involved predominantly in signaling through inhibition of adenylate cyclase
  • couple to their intracellular effector through distinct signaling pathways
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein receptor for the hormone galanin
    cell & other i5 linked to voltage gated calcium channel
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility to alcoholism
    Variant & Polymorphism SNP significant association with alcoholism that was driven by one SNP (rs3,091,367)
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS