Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | SOAT2 | contributors: mct - updated : 01-04-2019 |
HGNC name | sterol O-acyltransferase 2 |
HGNC id | 11178 |
|
DNA |
TYPE | functioning gene |
STRUCTURE | 21.05 kb 15 Exon(s) |
10 Kb 5' upstream gene genomic sequence study |
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regulatory sequence
text structure
| lack sterol regulatory elements in the promoter | |
MAPPING | cloned | Y | linked | status | provisional |
RNA |
TRANSCRIPTS | type | messenger |
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EXPRESSION |
Type | restricted |
expressed in | (based on citations) | ||||||||||||||||||||||||||||||||||||||||
organ(s) |
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cells |
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cell lineage
cell lines
| fluid/secretion
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at STAGE |
Text | liver |
PROTEIN |
PHYSICAL PROPERTIES
STRUCTURE
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motifs/domains
|
mono polymer | homomer , heteromer , dimer |
HOMOLOGY |
interspecies | homolog to murine Soat2 |
intraspecies | homolog to SOAT2 |
Homologene |
FAMILY | sterol-o-acyltransferase family |
CATEGORY | enzyme |
SUBCELLULAR LOCALIZATION | plasma membrane |
intracellular | |
intracellular,cytoplasm,organelle,membrane | |
intracellular,cytoplasm,organelle,endoplasmic reticulum | |
text | located in the rough endoplasmatic reticulum that catalyzes the synthesis of cholesteryl esters from cholesterol and long-chain fatty acids |
basic FUNCTION | |
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CELLULAR PROCESS |
PHYSIOLOGICAL PROCESS |
PATHWAY |
metabolism | lipid/lipoprotein |
signaling |
cholesterol |
a component |
INTERACTION |
DNA |
RNA |
small molecule |
protein |
cell & other |
REGULATION |
Other | transcriptionally regulated by cholesterol |
ASSOCIATED DISORDERS |
corresponding disease(s) |
Other morbid association(s) |
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Susceptibility |
Variant & Polymorphism
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Candidate gene
Marker
| Therapy target
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ANIMAL & CELL MODELS |