protein
| NS1 protein of parvovirus H-1 |
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70kDa heat shock cognate protein |
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interacting with MSTN (N-terminal signal peptide of myostatin is essential for its association with SGTA and the C-terminal region of SGTA containing the third TPR motif was indispensable for its interaction with myostatin) |
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interacts with the hinge region of AR |
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interacted with not only Hsp90alpha but also Hsp90beta |
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can bind to both Vpu and Gag of human immunodeficiency virus type 1 (HIV-1) and the overexpression of SGT in cells reduces the efficiency of HIV-1 particle release |
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SGTA actively promotes the deubiquitination of mislocalized proteins that are already covalently modified, thus reversing the actions of BAG6 and inhibiting its capacity to promote substrate-specific degradation |
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SGTA can bind either BAG6, or UBL4A, but not both at the same time |
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binding of SGTA to ADRM1 enables specific polypeptides to escape proteasomal degradation and/or selectively modulates substrate degradation |
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SGTA is a novel interacting partner of DKK3 |
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SGTA overexpression regulates BST2 expression and stability, thus providing insights into the function of SGTA in ER translocation and protein degradation |
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implicated as a co-chaperone and regulator of androgen and growth hormone receptor (AR, GHR) signalling |
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direct interaction between SGTA and the proteasome, mediated by the intrinsic proteasomal ubiquitin receptor ADRM1 (27827410) |
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critical role of HSPA8 in SV40 ER-to-cytosol penetration and SGTA controls HSPA8 to impact this process |