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FLASH GENE
Symbol BPHL contributors: mct/npt - updated : 30/09/2008
HGNC name biphenyl hydrolase-like (serine hydrolase; breast epithelial mucin-associated antigen)
HGNC id 1094
DNA
TYPE functioning gene
STRUCTURE 34.25 kb     8 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
8 - 1521 - 274 - Kim (2004)
EXPRESSION
Type widely
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestiveliver   highly
Reproductivefemale systemovary  highly
Urinarykidney   highly
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
intraspecies homolog to biphenyl hydrolase
Homologene
FAMILY
  • AB hydrolase superfamily
  • lipase family
  • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,mitochondria
    basic FUNCTION
  • serine hydrolase catalyzing the hydrolytic cleavage of carbon-carbon bonds
  • involved in the degradation of polychlorinated biphenyls
  • catalyzing the hydrolytic activation of the antiviral prodrugs valacyclovir and valganciclovir
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    text detoxication
    PATHWAY
    metabolism aminoacid , drug
    signaling
    aminoacid derivatives
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS