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FLASH GENE
Symbol RPL7 contributors: mct/npt - updated : 11-07-2007
HGNC name ribosomal protein L7
HGNC id 10363
DNA
TYPE functioning gene
STRUCTURE 2.30 kb     7 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked   status confirmed
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
7 - 866 - 248 - Robledo (2008)
EXPRESSION
Type ubiquitous
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestivepharynx   highly
 salivary gland   highly
Endocrinepancreas   highly
Hearing/Equilibriumearinnercochlea highly
Lymphoid/Immunetonsils   highly
Urinarybladder   highly
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Blood / hematopoieticbone marrow  highly
Connectivebone  highly
Epithelialbarrier/lining  highly
cells
SystemCellPubmedSpeciesStageRna symbol
Skin/Tegumentkeratinocyte
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
mono polymer homomer , dimer
HOMOLOGY
interspecies homolog to rattus Rpl7 (96.69 pc)
Homologene
FAMILY
  • ribosomal protein L30P family
  • CATEGORY RNA associated
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,cytosolic,ribosome
    basic FUNCTION
  • 60S ribosomal protein L7
  • binding to GC-rich structures in 28s rRNA and in mRNAs
  • playing a regulatory role in the translation apparatus ( inhibiting cell-free translation of mRNAs)
  • having an essential role for proliferation in all cells (Robledo 2008)
  • CELLULAR PROCESS protein, translation/synthesis
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
  • constituent of ribosome, large subunit
  • INTERACTION
    DNA
    RNA binding
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS