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FLASH GENE
Symbol MEGF9 contributors: npt/mct - updated : 03/12/2008
HGNC name multiple EGF-like-domains 9
HGNC id 3234
DNA
TYPE functioning gene
STRUCTURE 113.52 kb     8 Exon(s)
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
8 - 6297 - 639 - Humphray (2004)
EXPRESSION
Type widely
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
blood / hematopoieticspleen   highly
Cardiovascularheart   highly
Nervousbrainhindbraincerebellum predominantly
Respiratorylung   highly
cells
SystemCellPubmedSpeciesStageRna symbol
Nervousglia
Nervousneuron
cell lineage
cell lines
fluid/secretion
at STAGE
physiological period fetal
Text in the developing CNS (central nervous system) and PNS (peripheral nervous system
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • an N-terminal region with several potential O-glycosylation sites followed by five EGF-like domains, which are highly homologous with the short arms of laminins
  • membrane anchored protein with an EGF-like motif
  • three laminin type EGF-like motifs
  • HOMOLOGY
    Homologene
    FAMILY
    CATEGORY signaling , receptor
    SUBCELLULAR LOCALIZATION
    basic FUNCTION putative receptor, expressed in neuronal and non-neuronal tissues, that is regulated during development and could function as a guidance or signalling molecule
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS