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FLASH GENE
Symbol HABP4 contributors: mct - updated : 26/09/2008
HGNC name hyaluronan binding protein 4
HGNC id 17062
DNA
TYPE anonymous DNA segment
STRUCTURE 41.20 kb     8 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
8 - 2708 - 413 - Passos (2006)
EXPRESSION
Type widely
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestivemouthtongue  highly
Nervousbrain    
Visualeye   highly
cell lineage
cell lines
fluid/secretion
at STAGE
physiological period pregnancy
Text placenta
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • two conserved Gly/Arg-rich motif clusters (RGG/RXR box, that may be substrates for arginine-methylation by PRMT1
  • HOMOLOGY
    interspecies ortholog to chicken
    ortholog to murine Ihabp4
    intraspecies paralog to CDC37
    paralog to SERBP1
    Homologene
    FAMILY
    CATEGORY regulatory , antigen
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm
    intracellular,nucleus
    basic FUNCTION
  • putative regulator of cell cycle
  • with SERBP1, might be involved in nuclear functions like the remodeling of chromatin
  • CELLULAR PROCESS cell cycle
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • interacting with the C-terminal region of the chromatin-remodeling factor CHD3
  • interacting with PRMT1
  • partner of MEF2C protein and may be involved in the regulation of MEF2C at the onset of hypertrophy
  • cell & other
    REGULATION
    induced by induced upon activation of leukocytes transported in the nuclear compartment and activation of leukocytes
    Other phosphorylated at the serine and threonine residues upon cellular activation
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS