basic FUNCTION
| playing a role in craniofacial, brain, heart and limb development |
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playing a role in specifying neural systems involved in processing somatosensory information, as well as in face and body structure formation |
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acting as a growth regulator |
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key role in regulating the growth of stylopod by controlling chondrocyte maturation via RUNX2 and RUNX3 |
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may be regulating the expression of osteogenic genes and essential for the development and function of temporomandibular joint |
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essential for the formation of the sinoatrial valves and for the development of the pacemaking system |
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TBX5 function is critical for the expression of SHOX2 in cardiac tissues |
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required for normal skeletal, neural and muscular development in the forelimb at a similar early developmental stage in each tissue |
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