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FLASH GENE
Symbol PTPRU contributors: - updated : 27-09-2004
HGNC name protein tyrosine phosphatase, receptor type, U
HGNC id 9683
DNA
TYPE functioning gene
STRUCTURE 90.00 kb     31 Exon(s)
Genomic sequence alignment details
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked   status provisional
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
- - 5579 161 1436 - Yan
- - 5597 - 1442 - Yan
- - 5609 162 1446 - Yan
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Nervousbrain   highly
Reproductivefemale systemovary  highly
 male systemtestis  highly
 male systemprostate  highly
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Muscularstriatumskeletal  
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a MAM domain, an Ig-like region,
  • four fibronectin FN III repeats
  • a transmembrane segment
  • two phosphatase domains with a large extracellular motif
  • conjugated GlycoP
    HOMOLOGY
    interspecies ortholog to murine Ptpru (89 pc)
    Homologene
    FAMILY PTPR family
    CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     plasma membrane
    text type I membrane protein
    basic FUNCTION tyrosine phosphatase, receptor
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS