basic FUNCTION
| but likely excluded as the responsible gene |
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may be playing an essential role in cold-induced suppression of cell proliferation |
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may participate in the cell cycle regulation of normal endometrium and the loss of its expression may be involved in endometrial carcinogenesis |
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expression of CIRBP accelerates the G0/G1-to-S phase transition without affecting apoptosis |
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RBM3 and CIRBP are two established cold-shock proteins |
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CIRBP fine-tunes the cell-cycle progression of undifferentiated spermatogonia as well as fibroblasts and cancer cells by interacting with and suppressing kinase activity of DYRK1B to modulate the protein levels of CDKN1B and CCND1 |
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RNA-binding protein that is expressed in normal testis and down-regulated after heat stress |
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CIRBP and RBM3, are important regulators for the temperature entrained circadian gene expression |
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extracellular CIRBP is a detrimental factor in stimulating inflammation to cause neuronal damage in cerebral ischemia |