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FLASH GENE
Symbol PREPL contributors: mlc - updated : 26-10-2007
HGNC name prolyl endopeptidase-like
HGNC id 30228
DNA
TYPE functioning gene
STRUCTURE 43.00 kb     15 Exon(s)
MAPPING cloned Y linked N status provisional
Map pter - LRPPRC - SLC3A1 - PREPL - C2orf34 - SIX3 - cen
Authors Martens (2007)
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
- - 4636 - 665 - Martens (2006)
- - 4624 - 661 - Martens
- - 4822 - 727 - Martens
EXPRESSION
Type ubiquitous
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Cardiovascularheart   highly
Nervousbrain   highly
Urinarykidney   highly
Visualeye   highly
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Muscularstriatumskeletal  
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
mono polymer monomer
HOMOLOGY
interspecies homolog to moraxella proteinase 2
intraspecies homolog to prolyl endopeptidase and oligopeptidase B
Homologene
FAMILY peptidase S9A family
CATEGORY enzyme
SUBCELLULAR LOCALIZATION     intracellular
intracellular,cytoplasm,cytosolic
basic FUNCTION serine peptidase cleaving peptide bonds on the C-terminal side of prolyl residues within peptides that are up to approximately 30 amino acids long
CELLULAR PROCESS
PHYSIOLOGICAL PROCESS
PATHWAY
metabolism
signaling
a component
INTERACTION
DNA
RNA
small molecule
protein
cell & other
REGULATION
ASSOCIATED DISORDERS
corresponding disease(s) HCYS
Susceptibility
Variant & Polymorphism
Candidate gene
Marker
Therapy target
ANIMAL & CELL MODELS