basic FUNCTION
| has chemotactic activity for lymphocytes but not for monocytes or neutrophils |
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utilizes highly specific glycosaminoglycan-binding sites that represent potential targets for drug development |
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XCL1 may support vascular inflammation by induction of release of interleukin 8 in polymorphonuclear neutrophils |
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regulate independent and distinct steps during transcription initiation and elongation |
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C class chemokine also known as lymphotactin, is produced by T, NK, and NKT cells during infectious and inflammatory responses |
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XCL1 and XCR1 are constitutively expressed in the thymus and regulate the thymic establishment of self-tolerance and the generation of regulatory T cells |
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role of XCR1 and its Ligand XCL1 in Antigen Cross-Presentation byhuman dendritic cells |