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FLASH GENE
Symbol HIST1H1B contributors: npt - updated : 20/11/2008
HGNC name histone cluster 1, H1b
HGNC id 4719
DNA
TYPE functioning gene
SPECIAL FEATURE component of a cluster
STRUCTURE 0.86 kb     1 Exon(s)    1 Copie(s)
regulatory sequence Promoter (CAAT box) (TATA box)
text structure highly conserved H1/AC box
MAPPING cloned Y linked N status confirmed
regionally located in the small histone gene cluster
RNA
TRANSCRIPTS type messenger
text lacking the polyA tail but having instead a palindromic termination element
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
1 - 790 22.5 226 - -
EXPRESSION
Type
   expressed in (based on citations)
organ(s)
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES basic
STRUCTURE
motifs/domains
  • a globular DNA-binding domain
  • a N terminal lysine-rich region
  • a C terminal region with oligopeptide repeats enriched in serine, proline, lysine
  • HOMOLOGY
    interspecies ortholog to murine Hist1h1b
    Homologene
    FAMILY
  • histone H1/H5 family
  • CATEGORY regulatory , DNA associated , transcription factor
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus,chromatin/chromosome
    basic FUNCTION
  • involved in basal repression of gene expression
  • playing a role in the condensation of nucleosome chains into higher order structures
  • CELLULAR PROCESS nucleotide, chromatin organization, remodeling
    nucleotide, transcription, regulation
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA binding to a key regulatory element of MYOD
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS