protein
| interacting with TADA2L |
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interacting with CHEK1 (function in the same pathway to regulate the transcription of cell-cycle genes and thus promote cell-cycle progression) |
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ADA2a and ADA2b |
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binds more avidly to RELA after phosphorylation on Ser 468, an event that is dependent on IKK activity |
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interacting with CDC6 (mediates acetylation and site-specific phosphorylation of CDC6, both necessary for the relocalization of the protein to the cell cytoplasm in the S phase, as well as to regulate its stability) |
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binds to the 5prime proximal regions of SYK and BTK genes, suggesting that gene expressions of SYK and BTK are regulated by KAT2A |
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NUT can interact with additional HAT enzymes such as KAT5 and KAT2A to induce the histone hyperacetylation on chromatin |
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WDHD1 having remarkable capability to regulate the stability of KAT2A proteins and thereby histone H3 acetylation |
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functional link between KAT2A and WDHD1 essential for KAT2A protein stability and histone H3 acetylation, but also a potential role of WDHD1 in cancer |
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DTL and WDHD1 play an essential role in the regulation of KAT2A protein stability |
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PTGES3 regulates both KAT2A acetylase and HSF1 DNA binding activities |
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HDAC3 regulates cyclin A stability by counteracting the action of the acetylases KAT2A/KAT2B |
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inhibition of KAT2A protein catalytic activity by polyglutamine-expanded ATXN7 |
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SUPT20H-mediated suppression of KAT2A ubiquitination most likely occurs via nuclear sequestration of KAT2A |
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KAT2A and EBF1 participate in regulation of PRKCQ gene expression in an opposite manner in immature B cells |
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MYC interacts with the human STAGA coactivator complex via multivalent contacts with the KAT2A and TRRAP subunits |
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LAMTOR5 promotes the migration of breast cancer cells through modulating microtubule acetylation mediated by KAT2A |
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DDIT3 and KAT2A cooperatively up-regulate TNFRSF10A and TNFRSF10B |
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KAT2A regulates osteogenic differentiation of mesenchymal stem cells by inhibiting NFKB1 |
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ORC5 associates with the H3 histone acetyl transferase KAT2A, and this association enhances the chromatin-opening function of ORC5 |
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regulated DKK1 expression by acetylation of Histone H3 lysine 9 (H3K9) and Histone H3 lysine 14 (H3K14) at its promoter region |
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KAT2A/KAT2B acetylation of PLK4 prevents centrosome amplification |
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link between KAT2A and the FGF signaling pathway and specific KAT2A-MYC partnerships in gene regulation during early differentiation |
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ERCC3 interacts functionally with KAT2A, a histone acetyltransferase (HAT) that belongs to the hSAGA and hATAC complexes |
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tight connection between GTFIIH1 and KAT2A that controls higher-order chromatin structure and gene expression |
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KAT2A is a specific TFEB acetyltransferase, and acetylation by KAT2A results in the decrease in TFEB transcriptional activity |
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KAT2A regulates ZBTB16 through acetylation, mediates osteogenic differentiation, and affects orthodontic tooth movement |