basic FUNCTION
| cell sprouting and reorganization of actin skeleton |
|
possibly participating in receptor-mediated signal transduction at the plasma membrane |
|
plays a role in regulating voltage-gated Ca2+ channels and cytoskeletal reorganization |
|
endogenous GEM down-regulates the level of active RHOA and actin stress fibers |
|
plays an important role in normal beta-cell function by regulation of calcium signalling. |
|
small GTP-binding protein that plays a role in regulating Ca(2+) channels and cytoskeletal remodeling in interphase cells |
|
spindle-associated protein and is required for proper mitotic progression |
|
involved in regulation of voltage-gated calcium channel activity and inhibition of Rho kinase-mediated cytoskeletal reorganization, such as stress fiber formation and neurite retraction |
|
plays an important role in cell-to-cell viral transmission |
|
small guanosine triphosphate (GTP)-binding protein, involved in the regulation of voltage-gated calcium channel activity and cytoskeleton reorganization |
|
plays a crucial role in the regulation of cortical actin cytoskeleton that undergoes active remodeling during mitosis |
|
new role of GEM/GMIP/RHOA signaling in cortical actin regulation during early mitotic stages |