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FLASH GENE
Symbol AOAH contributors: npt/ - updated : 23-05-2005
HGNC name acyloxyacyl hydrolase (neutrophil)
HGNC id 548
DNA
TYPE functioning gene
STRUCTURE 211.42 kb     21 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
text precursor of two disulfide-linked subunits
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
21 - 2474 65.1 575 - -
EXPRESSION
Type
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestiveintestinelarge intestinecolon  
Endocrinethyroid    
cells
SystemCellPubmedSpeciesStageRna symbol
Blood/Hematopoieticleukocyte
Lymphoid/Immunemacrophage
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • lipase consensus sequence in large subunit saposin homology region in small subunit
  • mono polymer heteromer , dimer
    isoforms Precursor precursor of two disulfide-linked subunits
    HOMOLOGY
    interspecies homolog to murine Aoah
    Homologene
    FAMILY
    CATEGORY enzyme
    SUBCELLULAR LOCALIZATION
    basic FUNCTION
  • specifically hydrolyzing the secondary acyl chains of the liposaccharide found in the walls of gram-negative bacteria
  • two-subunit lipase
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS inflammation
    PATHWAY
    metabolism lipid/lipoprotein
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS