Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Orphanet | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | ITGA2 | contributors: mct - updated : 09-05-2007 |
HGNC name | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) |
HGNC id | 6137 |
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DNA |
TYPE | functioning gene |
STRUCTURE | 102.00 kb 30 Exon(s) |
10 Kb 5' upstream gene genomic sequence study |
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MAPPING | cloned | Y | linked | status | confirmed |
RNA |
TRANSCRIPTS | type | messenger |
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EXPRESSION |
Type | widely |
constitutive of |
expressed in | (based on citations) | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
organ(s) |
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tissue |
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cell lineage
cell lines
| fluid/secretion
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at STAGE |
physiological period | embryo |
Text | embryonic tissue at a lowly level |
PROTEIN |
PHYSICAL PROPERTIES
STRUCTURE
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conjugated | GlycoP |
mono polymer | heteromer , dimer |
isoforms | Precursor | a 1152 amino acids mature peptide (126.4 kDa) |
HOMOLOGY |
interspecies | homolog to chimpanzee ITGA2 (99.75 pc) |
homolog to rattus Itga2 (81.83 pc) | |
homolog to murine Itga2 (82.60 pc) |
Homologene |
FAMILY | integrin family |
CATEGORY | adhesion , antigen , receptor |
SUBCELLULAR LOCALIZATION | plasma membrane |
text | type 1 membrane protein |
basic FUNCTION | cell surface adhesion receptor mediating cell-adhesion to extra cellular matrix or to other cells,through hetero dimerization and connecting to the cytoskeleton and various signaling molecules within cells |
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