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FLASH GENE

Symbol

FABP6

contributors: - updated : 18-07-2005

HGNC name	fatty acid binding protein 6, ileal (gastrotropin)
HGNC id	3561

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

DNA

TYPE	functioning gene
STRUCTURE	9.00 kb     4 Exon(s)

10 Kb 5' upstream gene genomic sequence study

MAPPING

cloned

Y

linked

status

provisional

RNA

TRANSCRIPTS	type	messenger

EXPRESSION

Type

constitutive of

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Digestive intestine small intestine ileum   highly

tissue

System Tissue Tissue level 1 Tissue level 2 Level Pubmed Species Stage Rna symbol Epithelial         Membrane mucous lamina propria intestine villi

cell lineage

cell lines

fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains

repeated structure + topology beta barrel and remarkable structural signature

HOMOLOGY

interspecies

homolog to murine Fabp6

Homologene

FAMILY

lipocalin, calycin family

CATEGORY

regulatory , transport carrier

SUBCELLULAR LOCALIZATION	intracellular
	intracellular,cytoplasm,cytosolic

basic FUNCTION	fatty acid binding protein 6, ileal lipid-binding protein, intestinal bile acid binding protein
	implicated in the enterohepatic circulation of bile acids and, hence, in cholesterol homeostasis

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

RNA

small molecule

protein

cell & other

REGULATION

Other

regulated by NR1H3

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS