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FLASH GENE
Symbol CHRM5 contributors: mct - updated : 08-04-2015
HGNC name cholinergic receptor, muscarinic 5
HGNC id 1954
DNA
TYPE functioning gene
STRUCTURE 1.00 kb     1 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned   linked   status provisional
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type restricted
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestiveintestinelarge intestinecolon  
Nervousbrain    
Reproductivefemale systemuterus   
 male systemtestis   
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
seven transmembrane segments (7TM) receptor
HOMOLOGY
Homologene
FAMILY G protein coupled receptor superfamily, k1 cholinergic receptor, muscarinic 5
CATEGORY receptor , transport channel
SUBCELLULAR LOCALIZATION     plasma membrane
basic FUNCTION mediating various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins
CELLULAR PROCESS
PHYSIOLOGICAL PROCESS
PATHWAY
metabolism
signaling
a component
INTERACTION
DNA
RNA
small molecule
protein
  • direct physical interaction between CHRM5 and the AP-3 adaptor complex regulator AGAP1
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS