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FLASH GENE
Symbol PLCXD1 contributors: mct - updated : 07-09-2015
HGNC name phosphatidylinositol-specific phospholipase C, X domain containing 1
HGNC id 23148
DNA
TYPE functioning gene
STRUCTURE 27.03 kb
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
7 - 5320 - 323 - 2012 22732399
EXPRESSION
Type
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Cardiovascularheart     Homo sapiens
Digestiveintestinelarge intestinecolon   Homo sapiens
 intestinesmall intestine    Homo sapiens
Lymphoid/Immunethymus     Homo sapiens
Nervousbrain   predominantly Homo sapiens
Urinarykidney    Homo sapiens
cells
SystemCellPubmedSpeciesStageRna symbol
Blood/Hematopoieticleukocyte Homo sapiens
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • only the X-domain of the normal X and Y catalytic domains found in all known mammalian PLC family members and are also devoid of all other regulatory domains
  • HOMOLOGY
    Homologene
    FAMILY
    CATEGORY
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm
    basic FUNCTION
  • may function as active phosphodiesterases as they are able to increase the turnover of inositol phosphate from some unknown phospholipid pool
  • it is one of only 29 pseudo-autosomal genes that are present on both X (Xp22.33) and Y (Yp11.32) chromosomes
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS