basic FUNCTION
| promotes ubiquitylation of CCP110, thereby destabilizing this protein |
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counteracts accumulation of CCP110, thereby maintaining normal centriolar homeostasis and preventing formation of ectopic MTOCs (microtubular organizing centres) |
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is a protein that interacts with CCP110, a centrosomal protein that regulates centrosome duplication |
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centrosome-targeted NEURL4 was sufficient to restore ciliogenesis in cells with manipulated daughter centrioles |
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early during ciliogenesis, NEURL4 transiently associated with the mother centriole in a process that required mother-daughter centriole proximity |