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FLASH GENE
Symbol MCTP2 contributors: mct/npt - updated : 07-09-2009
HGNC name multiple C2 domains, transmembrane 2
HGNC id 25636
DNA
TYPE functioning gene
STRUCTURE 180.83 kb     22 Exon(s)
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
22 - 7637 - 878 - Shin (2005)
- - 7637 - 823 - Shin (2005)
- - 2009 - 306 - Shin (2005)
EXPRESSION
Type
   expressed in (based on citations)
organ(s)
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • variable N-terminal sequence
  • three C2 domains, anchored in the membrane by two closely spaced transmembrane regions and representing Ca(2+)-binding but not phospholipid-binding modules (second C2 domain including a perfect Ca2+/phospholipid-binding consensus sequence)
  • HOMOLOGY
    Homologene
    FAMILY
  • multiple C2 domain and transmembrane region proteins family
  • CATEGORY regulatory
    SUBCELLULAR LOCALIZATION     plasma membrane
    basic FUNCTION
  • involved in intercellular signal transduction and synapse function (Djurovic 2009)
  • possible involvement of MCTP2 as a potential novel susceptibility gene for schizophrenia (Djurovic 2009)
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS