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FLASH GENE
Symbol INCA1 contributors: mct - updated : 04-03-2009
HGNC name inhibitor of CDK, cyclin A1 interacting protein 1
HGNC id 32224
DNA
TYPE functioning gene
STRUCTURE 9.48 kb     9 Exon(s)
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
9 - 1574 - 236 - 2004 15159402
8 - 1404 - 221 -
8 - 1287 - 236 - -
8 - 1242 - 221 - -
EXPRESSION
Type
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Reproductivemale systemtestis    Homo sapiens
cell lineage
cell lines bladder carcinoma cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
Homologene
FAMILY
  • INCA family
  • CATEGORY signaling
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm
    intracellular,nucleus
    text C9orf9 and INCA1 were found to be co-localized principally in the cytoplasm
    basic FUNCTION
  • plays a role in several signaling pathways important for cell cycle control and meiosis
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • substrates for the cyclin A1-CDK2 kinase complex
  • interaction between C9orf9 and INCA1
  • ING5 is a growth suppressor with suppressed expression in AML whose functions depend on its interaction with INCA1
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS