Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | CCDC88B | contributors: mct - updated : 05-02-2009 |
HGNC name | coiled-coil domain containing 88B |
HGNC id | 26757 |
|
DNA |
TYPE | functioning gene |
STRUCTURE | 17.31 kb 27 Exon(s) |
MAPPING | cloned | Y | linked | N | status | provisional |
RNA |
TRANSCRIPTS | type | messenger |
---|
|
EXPRESSION |
Type | widely |
tissue |
|
cells |
|
cell lineage
cell lines
| fluid/secretion
| |
at STAGE |
PROTEIN |
PHYSICAL PROPERTIES
STRUCTURE
| |
motifs/domains
| |
| |
|
HOMOLOGY |
Homologene |
FAMILY | |
|
CATEGORY | unknown/unspecified |
SUBCELLULAR LOCALIZATION |
basic FUNCTION | |
|
CELLULAR PROCESS |
PHYSIOLOGICAL PROCESS |
PATHWAY |
metabolism |
signaling |
a component | CCDC88B/GRP78 interaction controls the IRE1-JNK signaling pathway to protect endothelial cells against ER stress-induced apoptosis in pathological contexts such as atherosclerosis and vascular endothelial dysfunction |
INTERACTION |
DNA |
RNA |
small molecule |
protein | |
|
cell & other |
REGULATION |
induced by | upon ER stress |
ASSOCIATED DISORDERS |
ANIMAL & CELL MODELS |