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FLASH GENE
Symbol DRGX contributors: mct/ npt - updated : 22/10/2008
HGNC name dorsal root ganglia homeobox
HGNC id 21536
DNA
TYPE functioning gene
STRUCTURE 25.75 kb     6 Exon(s)
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
6 - 807 - 268 - Saito (1995)
EXPRESSION
Type restricted
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Nervousgangliasensory gangliadorsal root  
cell lineage
cell lines
fluid/secretion
at STAGE
physiological period embryo
Text in embryonic dorsal root ganglion (DRG) and dorsal horn neurons
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
HOMOLOGY
Homologene
FAMILY
  • paired homeobox family
  • CATEGORY transcription factor
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus
    basic FUNCTION
  • may function in the establishment or maintenance of connectivity between some of these neurons and their central nervous system targets
  • playing a role in early postnatal survival of normally generated small primary afferent neurons innervating various kinds of peripheral tissues
  • paired domain transcription factor that is necessary for the assembly of the nociceptive circuitry in the spinal cord dorsal horn
  • required for the establishment of the first neuronal sensory relay along development
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS