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FLASH GENE
Symbol RLF contributors: - updated : 09-12-2005
HGNC name rearranged L-myc fusion sequence
HGNC id 10025
DNA
TYPE functioning gene
STRUCTURE 80.00 kb     7 Exon(s)
Genomic sequence alignment details
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status tentative : very preliminary evidence
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestiveliver    
Endocrinepancreas    
Nervousspinal cord    
Reproductivemale systemprostate   
Urinarykidney    
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Muscularstriatumskeletal  
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
Zn-15 related zinc finger protein
HOMOLOGY
Homologene
FAMILY krueppel family oC2H2-type zinc- finger proteins.
CATEGORY transcription factor
SUBCELLULAR LOCALIZATION     intracellular
intracellular,nucleus
basic FUNCTION may be functioning as a transcription factor
CELLULAR PROCESS nucleotide, transcription
PHYSIOLOGICAL PROCESS
PATHWAY
metabolism
signaling
a component
INTERACTION
DNA
RNA
small molecule
protein
cell & other
REGULATION
ASSOCIATED DISORDERS
corresponding disease(s)
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
tumoral   translocation    
rearranged in small cell lung carcinoma
Susceptibility to oesophageal cancer from smoking and heavy drinking
Variant & Polymorphism other genotype LL protecting against lung cancer
Candidate gene
Marker
Therapy target
ANIMAL & CELL MODELS