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FLASH GENE
Symbol AASDH contributors: npt - updated : 25-06-2008
HGNC name aminoadipate-semialdehyde dehydrogenase
HGNC id 23993
DNA
TYPE functioning gene
STRUCTURE 49.00 kb     15 Exon(s)
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
15 - 3573 - 1098 - Watkins (2007)
EXPRESSION
Type widely
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Endocrineadrenal gland   highly
Hearing/Equilibriumear   highly
Nervousnerve   highly
Respiratoryrespiratory tracttrachea  highly
cell lineage
cell lines colon adenocarcinoma
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • an AMP-binding domain
  • a phosphopantetheine-binding domain
  • six PQQ-binding motifs
  • HOMOLOGY
    Homologene
    FAMILY
  • acyl-coenzyme A synthetases family
  • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     plasma membrane
    basic FUNCTION
  • plays a unique role, directing the acyl-CoA product to a specific metabolic fate
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS