basic FUNCTION
| RING-finger protein, ubiquitin ligase for SLC22A18 that can function in concert with the ubiquitin-conjugating enzyme UBE2E1 |
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RNF167 is a selective regulator of AMPAR-mediated neurotransmission |
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is an endosomal ubiquitin ligase that regulates AMPAR-mediated synaptic transmission |
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influences the activity-dependent ubiquitination of neuronal AMPARs and regulates AMPA receptor-mediated synaptic transmission |
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implicated in the regulation of cellular endosome trafficking |
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RNF167 plays a crucial role as an E3 ubiquitin ligase targeting ARL8B to regulate lysosome positioning and endocytic trafficking |