Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | FBLN2 | contributors: mct - updated : 05-12-2012 |
HGNC name | fibulin 2 |
HGNC id | 3601 |
|
DNA |
TYPE | functioning gene |
STRUCTURE | 89.30 kb 18 Exon(s) |
10 Kb 5' upstream gene genomic sequence study |
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regulatory sequence | Binding site |
text structure | 18 exons coding |
MAPPING | cloned | Y | linked | Y | status | confirmed |
RNA |
TRANSCRIPTS | type | messenger |
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EXPRESSION |
Type | widely |
expressed in | (based on citations) |
organ(s) |
cell lineage
cell lines
| fluid/secretion
| |
at STAGE |
physiological period | embryo, pregnancy |
Text | |
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PROTEIN |
PHYSICAL PROPERTIES
STRUCTURE
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motifs/domains
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conjugated | GlycoP |
mono polymer | homomer , trimer |
HOMOLOGY |
interspecies | homolog to murine Fbln2 |
homolog to Drosophila CG10323 | |
homolog to C.elegans F56H11.1a |
Homologene |
FAMILY |
CATEGORY | regulatory , structural protein |
SUBCELLULAR LOCALIZATION | extracellular |
text | |
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basic FUNCTION | |
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CELLULAR PROCESS |
PHYSIOLOGICAL PROCESS |
PATHWAY |
metabolism |
signaling |
COL6A1, COL6A2, CRELD1, FBLN2, FRZB, and GATA5 harboring purportedly deleterious case-specific variants in atrioventricular septal defects (AVSD)are associated in some way with VEGFA |
a component |
INTERACTION |
DNA |
RNA |
small molecule | metal binding, |
protein | |
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cell & other |
REGULATION |
ASSOCIATED DISORDERS |
corresponding disease(s) |
Other morbid association(s) |
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Susceptibility | to atrioventricular septal defects |
Variant & Polymorphism
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Candidate gene
Marker
| Therapy target
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ANIMAL & CELL MODELS |