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FLASH GENE
Symbol GRIP2 contributors: mct - updated : 22-04-2011
HGNC name glutamate receptor interacting protein 2
HGNC id 23841
DNA
TYPE functioning gene
STRUCTURE 52.97 kb     25 Exon(s)
MAPPING cloned N linked N status provisional
RNA
TRANSCRIPTS type
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
25 - 7977 - 1140 - 2000 11214971
EXPRESSION
Type
   expressed in (based on citations)
organ(s)
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
Homologene
FAMILY
CATEGORY regulatory
SUBCELLULAR LOCALIZATION     plasma membrane
    intracellular
intracellular,cytoplasm,cytosolic
basic FUNCTION
  • may serve to organize macromolecular complexes, linking AMPA-Rs and other membrane proteins to the cytoskeleton and membrane trafficking and signal transduction pathways
  • multi-PDZ domain-containing protein that interact with the C-termini of AMPA-R GRIA2 and GRIA3 subunits
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein bind to the C-termini of AMPA-R GRIA2 and GRIA3 subunits
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS