basic FUNCTION
| eliciting Ca2+ desensitization in smooth muscle |
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playing a roles in cGMP/cAMP-mediated adaptations to exercise through mechanisms involving direct modulation of contractile activity |
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able to modulate the contractile activity of both smooth and skeletal muscle |
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having a unique position to influence thin-filament structure as well as Ca2+-regulated contraction |
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plays a role in promoting relaxation as well as adaptive responses to exercise, pregnancy and sexual development in smooth and skeletal muscle |
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possible restrictive control of its expression in non-muscle cells |
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plays a major role in pregnancy to promote adaptive responses in USM (uterine smooth muscle) and this process is specifically mediated through interactions of SMTNL1 with PGR |
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key player in USM plasticity mediated through the sex-related hormones |