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FLASH GENE
Symbol FBXW9 contributors: - updated : 14-06-2006
HGNC name F-box and WD-40 domain protein 9
HGNC id 28136
DNA
TYPE functioning gene
STRUCTURE 7.00 kb     10 Exon(s)
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestivesalivary gland    
Reproductivefemale systemuteruscervix  
 male systemprostate   
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Connectivebone   
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • one F-box domain
  • six WD repeats
  • HOMOLOGY
    interspecies homolog to rattus Fbxw9 (83.3pc)
    homolog to murine Fbxw9 (82.0pc)
    Homologene
    FAMILY F-box protein family
    CATEGORY adaptor
    SUBCELLULAR LOCALIZATION
    basic FUNCTION involved in ubiquitination
    CELLULAR PROCESS protein, degradation
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component component of SCF complexes, formed by SKP1, cullin and F-box proteins
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • interacting with SKIP1 through the F-box
  • interacting with ubiquitination targets
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS