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FLASH GENE
Symbol TXNL4A contributors: mct - updated : 07-01-2015
HGNC name thioredoxin-like 4A
HGNC id 30551
DNA
TYPE functioning gene
STRUCTURE 15.68 kb     3 Exon(s)
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
3 - 1415 - 142 - -
EXPRESSION
Type ubiquitous
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestivepharynx   highly
Endocrinepancreas    
Lymphoid/Immunetonsils   highly
Reproductivefemale systemuterus   
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
interspecies ortholog to yeast Dib1
Homologene
FAMILY
CATEGORY RNA associated
SUBCELLULAR LOCALIZATION     intracellular
intracellular,cytoplasm
intracellular,nucleus,nucleoplasm
text spliceosome complex
basic FUNCTION
  • involved in pre-mRNA splicing, and participating in different multisubunit complexes and biological processes
  • besides its function in pre-mRNA splicing, is a peptidase and has autocleavage activity
  • CELLULAR PROCESS nucleotide, RNA splicing
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • PQBP1 binds to TXNL4A via a continuous 23-AAs segment within its C-terminal domain
  • TXNL4A hydrophobic groove recognizes a YxxPxxVL motif in PQBP1
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s) BMKS
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS