basic FUNCTION
| inhibits herpes simplex virus replication (Akhova 2005) |
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activating the TrkA promoter and inducing the expression of endogenous TrkA (Valderrama 2008) |
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inducing the expression of TrkA in medulloblastoma cells and causing their differenciation or apoptosis (Valderrama 2009) |
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inhibits GR, CAR and HNF4 alpha-mediated transactivation, corepressor of nuclear receptors via competition with coactivators and the recruitment of HDACs (Xie 2009) |
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orphan nuclear receptor NR0B2-interacting protein, regulating NR0B2-repressed estrogen receptor transactivation (Xie 2009) |
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cooperates synergistically with HEY1 to enhance TP53 transcriptional activity |
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CREBZF may participate in the modulation of p53 tumor suppressor function |