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FLASH GENE
Symbol CELA2A contributors: np/ - updated : 25-07-2005
HGNC name chymotrypsin-like elastase family, member 2A
HGNC id 24609
DNA
TYPE functioning gene
STRUCTURE 15.36 kb     8 Exon(s)
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
8 - 934 28 269 - -
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Endocrinepancreas   specific
cell lineage
cell lines
fluid/secretion
at STAGE
physiological period fetal
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a signal peptide
  • an activation petptide
  • a peptidase S1 domain
  • isoforms Precursor of a 241aa mature enzyme
    HOMOLOGY
    interspecies ortholog to rattus Ela2
    Homologene
    FAMILY
  • serine protease family
  • peptidase S1 family
  • elastase subfamily
  • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION extracellular
    text secreted as a zymogen
    basic FUNCTION
  • pancreatic elastase activity
  • CELLULAR PROCESS protein, degradation
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • interacting with CPA1
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS