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FLASH GENE
Symbol HNRNPUL1 contributors: mct/npt - updated : 22-04-2009
HGNC name heterogeneous nuclear ribonucleoprotein U-like 1
HGNC id 17011
DNA
TYPE functioning gene
STRUCTURE 43.69 kb     15 Exon(s)
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
15 - 4201 - 856 - Kzhyshkowska, Olsen (2006)
- - 3716 - 804 - Kzhyshkowska, Olsen (2006)
- - 1800 - 122 - Kzhyshkowska, Olsen (2006)
15 - 3714 - 756 - Kzhyshkowska, Olsen (2006)
EXPRESSION
Type ubiquitous
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestivemouth   highly
Lymphoid/Immunetonsils   highly
Reproductivefemale systemovary  highly
cells
SystemCellPubmedSpeciesStageRna symbol
Skin/Tegumentepithelial cell
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
Homologene
FAMILY
  • heterogeneous nuclear ribonucleoprotein (hnRNP) family
  • CATEGORY RNA associated
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus
    basic FUNCTION
  • may play an important role in nucleocytoplasmic RNA transport
  • playing a role as a key regulator of ATR signaling pathways activated during Adenovirus infection (Blackford 2008)
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA RNA binding
    small molecule
    protein
  • binds specifically to adenovirus E1B-55kDa oncoprotein
  • targeted by adenovirus (Ad) E1B-55K during infection (Blackford 2008)
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility to early-onset myocardial infarction (MI)
    Variant & Polymorphism SNP associated with early-onset MI (Shiffman 2006)
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS