basic FUNCTION
| playing a critical role for proper assembly of the HIV-1 capsid |
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playing a role in RNase L inhibition, human immunodeficiency virus (HIV1)capsid maturation, translation initiation, and ribosome biosynthesis |
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role in eukaryotic translation has been linked to several stages during protein synthesis, including initiation and most recently termination and ribosome recycling |
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required for the assembly of the HIV and SIV gag polypeptides |
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promotes eukaryotic ribosomal recycling over a wide range of Mg(2+) concentrations |
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play an important role in the pathogenesis of human small cell lung cancer cell |
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essential and highly conserved protein that requires notoriously ROS-labile cofactors (Fe-S clusters) for its functions in protein synthesis |
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its function is a primary target of ROS action |
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is closely connected with the pathogenesis and development of esophageal carcinoma, which act through the cellular pathways of RNASEL |
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ribosome-recycling factor important for translation termination in mammalian cells |
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is crucial for ribosome recycling and controls ribosome homeostasis |
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is involved in histone biosynthesis and DNA replication and therefore is essential for normal S phase progression |
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erythroid cells and platelets ribosomes accumulate as a result of the natural loss of the ribosome recycling factor ABCE1 during terminal differentiation |