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FLASH GENE
Symbol THADA contributors: SGE/npt - updated : 13-07-2010
HGNC name thyroid adenoma associated
HGNC id 19217
DNA
TYPE functioning gene
STRUCTURE 365.21 kb     38 Exon(s)
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
38 - 6134 - 1953 - Rippe (2003)
38 - 6346 - 1953 - Rippe (2003)
24 exons
EXPRESSION
Type
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestiveintestinesmall intestine   
 liver   highly
 stomach    
Endocrinepancreas    
 thyroid    
Lymphoid/Immunethymus    
Reproductivefemale systemuterus   
 male systemtestis   
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
conjugated PhosphoP
HOMOLOGY
interspecies homolog to rattus Thada (79.8pc)
homolog to murine Thada (79.0pc)
Homologene
FAMILY
  • THADA family
  • CATEGORY receptor membrane
    SUBCELLULAR LOCALIZATION     plasma membrane
        intracellular
    intracellular,cytoplasm
    basic FUNCTION
  • a death receptor-interacting protein
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Other morbid association(s)
    TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
    tumoral   translocation    
    aberrantly rearranged in thyroid adenomas (Drieschner 2007)
    Susceptibility to Polycystic ovary syndrome (PCOS)
    Variant & Polymorphism SNP associated with Polycystic ovary syndrome (PCOS)
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS