SUBCELLULAR LOCALIZATION
| intracellular
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| intracellular,cytoplasm,organelle,membrane
|
| intracellular,cytoplasm,organelle,endosome
|
| intracellular,cytoplasm,cytosolic
|
text
| resides in a late endosome microdomain together with mannose 6-phosphate receptors (MPRs) and RAB9A |
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occurs in the cytosol and on endosomal membranes, and shuttles between these two compartment |
basic FUNCTION
| lipid droplet protein that regulate cellular neutral lipid stores |
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required for the transport of mannose 6-phosphate receptors (MPR) from endosomes to the trans-Golgi network |
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delivering lysosomal hydrolase from the Golgi to endosomes and then return to the Golgi complex |
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involved in lipid droplets |
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cytosolic protein that is essential for the transport of mannose 6-phosphate receptors (MPRs) from endosomes to the trans-Golgi |
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has apolipoprotein-like properties and reorganizes liposomes into small lipid discs |
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may act as a carrier protein for free fatty acids and in this way participates in conversion of macrophages into foam cells |
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can reorganize liposomes into small lipid discs, and it is recruited to lipid droplets |